Potential Toxicity of Indigofera tinctoria Synthesized Iron Nanoparticles against Aedes aegypti
DOI:
https://doi.org/10.55446/IJE.2024.1568Keywords:
Dengue vector, Aedes aegypti nanotechnology, medicinal plant, larvicidal, histology, Indigofera tinctoria, morphological analysis, fluorescence, biosynthesis, green nanoparticles.Abstract
Mosquitoes are the most important single category of insects, killing millions of people worldwide each year by spreading a variety of diseases. The principal dengue vector Aedes aegypti, is expected to infect 2.5 billion people worldwide, or more than 40% of the world’s population. According to a WHO survey, 50-100 million cases are reported globally each year. Extensive fumigation of synthetic pesticides to control the mosquito vector in Pakistan during each post-monsoon season greatly increased environmental contamination and the loss of beneficial insects from urban environments. This study looked into the larvicidal and pupicidal efficiency of green synthesized iron nanoparticles against Ae. aegypti. Nanoparticles were subjected to several analyses, including UV-Vis, FTIR, FESEM, EDAX, XRD, Zeta Potential, and DLS. Ae. aegypti, the predominant dengue mosquito, was studied for its larvicidal and pupicidal activities. Indigofera tinctoria produced iron nanoparticles with LC50 values ranging from 4.468 ppm (I instar larvae) to 7.952 ppm (pupae). Laboratory experimental studies on larval body tissues, particularly fat cells, fingernail skin and midgut have been carried out. It has been determined the plant synthesis of iron nanoparticles are harmful to Ae. aegypti larval.
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Baeshen R S, Baz M M. 2023. Efficacy of Acacia nilotica, Eucalyptus camaldulensis, and Salix safsafs on the mortality and development of two vector-borne mosquito species, Culex pipiens and Aedes aegypti, in the laboratory and field. Heliyon 9(5).
Benelli G, Caselli A, Canale A. 2017. Nanoparticles for mosquito control: Challenges and constraints. Journal of King Saud University-Science 29(4): 424-35.
Brito A F, Machado L C, Oidtman R J, Siconelli M J, Tran Q M, Fauver J R, Carvalho R D, Dezordi F Z, Pereira M R, de Castro-Jorge L A, Minto E C. 2021. Lying in wait: The resurgence of dengue virus after the Zika epidemic in Brazil. Nature communications 12(1):2619.
Demirezen D A, Yıldız Y Ş, Yılmaz D D. 2019. Amoxicillin degradation using green synthesized iron oxide nanoparticles: Kinetics and mechanism analysis. Environmental Nanotechnology, Monitoring and Management 11: 100219.
dos Santos Correia P R, de Freitas J D, Zeoly LA, Porto R S, da Paz Lima D J. 2023. Discovery and structure-activity relationship of Morita-Baylis-Hillman adducts as larvicides against dengue mosquito vector, Aedes aegypti (Diptera: Culicidae). Bioorganic and Medicinal Chemistry 90: 117315.
Dusfour I, Vontas J, David J P, Weetman D, Fonseca D M, Corbel V, Raghavendra K, Coulibaly M B, Martins A J, Kasai S, Chandre F. 2019. Management of insecticide resistance in the major Aedes vectors of arboviruses: Advances and challenges. PLoS Neglected Tropical Diseases 13(10): 0007615.
Esam J A L, Kalifawi. 2015. Green synthesis of magnetite iron oxide nanoparticles by using Al-Abbas’s (AS) hund fruit (Citrus medica) var Sarcodactylis Swingle extract and used in Al-’alqami river water treatment. Journal of Natural Sciences Research ISSN 2224-3186 (paper) ISSN 2225-0921 (Online) 5: 20.
Farrukh M A, Ali S, Rahman M K. 2013. Photodegradation of 2,4,6-trinitrophenol catalyzed by Zn/ MgO nanoparticles prepared in aqueous-organic medium. Korean Journal of Chemical Engineering 30(11): 2100-2107.
Finney D J. 1971. Probit analysis. Cambridge University Press, London. pp. 68-78.
Ge Y, Zhang Y, He S, Nie F, Teng G, Gu, N. 2009. Fluorescence modified chitosan-coated magnetic nanoparticles for high-efficient cellular imaging. Nanoscale Research Letters 4(4): 287-295.
Girard M, Nelson C B, Picot V, Gubler D J. 2020. Arboviruses: A global public health threat. Vaccine 38(24): 3989-94.
Kjanijou M, Jiraungkoorskul K, Kosai P, Jiraungkoorskul W. 2012. Effect of Murraya paniculata leaf extract against Culex quinquefasciatus larva. Asian Journal of Biological Sciences 5(4): 201-8.
Messina J P, Brady O J, Golding N, Kraemer M U, Wint G W, Ray S E, Pigott D M, Shearer FM, Johnson K, Earl L, Marczak L B. 2019. The current and future global distribution and population at risk of dengue. Nature Microbiology 4(9): 1508-15.
Noruzi M, Zare D, Davoodi D. 2012. A rapid biosynthesis route for the preparation of gold nanoparticles by aqueous extract of cypress leaves at room temperature. Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy 94: 84-88
Pathak V M, Verma V K, Rawat B S, Kaur B, Babu N, Sharma A, Dewali S, Yadav M, Kumari R, Singh S, Mohapatra A. 2022. Current status of pesticide effects on environment, human health and it’s eco-friendly management as bioremediation: A comprehensive review. Frontiers in Microbiology 2833.
Phanse Y, Dunphy B M, Perry J L, Airs P M, Paquette C C, Carlson J O, Xu J, Luft J C, DeSimone J M, Beaty B J, Bartholomay L C. 2015. Biodistribution and toxicity studies of PRINT hydrogel nanoparticles in mosquito larvae and cells. PLoS Neglected Tropical Diseases 9(5): 0003735.
Rajaganesh R, Murugan K, Panneerselvam C, Jayashanthini S, Roni M, Suresh U, Trivedi S, Rehman H, Higuchi A, Nicoletti M, Benelli G. 2016. Fern-synthesized silver nanocrystals: towards a new class of mosquito oviposition deterrents?. Research in Veterinary Science 109:40-51.
Rees E E, Petukhova T, Mascarenhas M, Pelcat Y, Ogden N H. 2018. Environmental and social determinants of population vulnerability to Zika virus emergence at the local scale. Parasites and vectors 11(1): 1-3.
Srinivasan S, Wankhar W, Rathinasamy S, Rajan R. 2016. Free radical scavenging potential and HPTLC analysis of Indigofera tinctoria linn (Fabaceae). Journal of Pharmaceutical Analysis 6(2):125-31.
Thompson R, Martin Del Campo J, Constenla D. 2020. A review of the economic evidence of Aedes-borne arboviruses and Aedes-borne arboviral disease prevention and control strategies. Expert Review of Vaccines 19(2): 143-62.
Vivekanandhan P, Venkatesan R, Ramkumar G, Karthi S, Senthil-Nathan S, Shivakumar M S. 2018. Comparative analysis of major mosquito vectors response to seed-derived essential oil and seed pod-derived extract from Acacia nilotica. International Journal of Environmental Research and Public Health 15(2):388.
World Health Organization. 2022. Dengue and Severe Dengue. https://www. who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue.
Yew Y P, Shameli K, Miyake M, Kuwano N, Bt Ahmad Khairudin N B, Bt Mohamad S E, Lee KX. 2016. Green synthesis of magnetite (Fe3O4) nanoparticles using seaweed (Kappaphycus alvarezii) extract. Nanoscale Research Letters 11:1-7.
Zargham F, Afzal M, Rasool K, Manzoor S, Qureshi N A. 2023. Larvicidal activity of green synthesized iron oxide nanoparticles using Grevillea robusta Cunn. leaf extract against vector mosquitoes and their characterization. Experimental Parasitology 108586.
Zeng Z, Zhan J, Chen L, Chen H, Cheng S. 2021. Global, regional, and national dengue burden from 1990 to 2017: A systematic analysis based on the global burden of disease study 2017. eClinicalMedicine 32: 100712.
